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1996-03-04
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Document 0637
DOCN M9640637
TI Health values of patients infected with human immunodeficiency virus.
Relationship to mental health and physical functioning.
DT 9604
AU Tsevat J; Solzan JG; Kuntz KM; Ragland J; Currier JS; Sell RL; Weinstein
MC; Department of Medicine, Beth Israel Hospital, Harvard Medical;
School, Boston, MA, USA.
SO Med Care. 1996 Jan;34(1):44-57. Unique Identifier : AIDSLINE
MED/96142309
AB To assess the health values of patients infected with human
immunodeficiency virus (HIV) and examine the relationships between their
health values and health status at two points in time, the authors
sought to determine whether patients' physical and mental health
statuses were good predictors of how they valued their current state of
health. One hundred thirty-nine patients with various stages of HIV
infection were interviewed in a prospective cohort study based in a
primary care practice of a community-based teaching hospital. Patients
were interviewed twice at 6-month intervals using three health value
measures--the time trade off, rating scale, and Quality of Well-being
Scale--and three health status measures: the 18-item Mental Health
Inventory, the Dyspnea-Fatigue Index, and the Medical Outcomes Study
SF-36 Health Survey. The health status of HIV-infected patients was
compromised and, with the exception of mental health, generally was
worse among patients with more advanced HIV-infection. Rating scale and
Quality of Well-being Scale scores were related inversely to disease
stage, but time-trade off scores generally were higher regardless of
disease stage. Health value measures showed moderate relationships with
measures of physical functioning (r = 0.34-0.68) but only a fair
relationship with mental health (r = 0.00-0.48). The health status of
HIV-infected patients who remained asymptomatic or remained symptomatic
but without developing acquired immunodeficiency syndrome (AIDS) changed
little over 6 months, whereas the health status of patients with AIDS
and of patients manifesting progression of HIV-infection deteriorated
over time. In contrast, health values, particularly time-tradeoff
scores, remained stable even in the face of changes in health status and
disease progression. With the exception of mental health, the impact of
HIV infection on health status tends to parallel the clinical stage of
disease. Health values of HIV-infected patients, however, generally are
high and correlate better with physical functioning than with mental
health.
DE *Activities of Daily Living Adult *Attitude to Health Female *Health
Status Human HIV Infections/PHYSIOPATHOLOGY/*PSYCHOLOGY Male
Massachusetts *Mental Health Predictive Value of Tests Prospective
Studies Quality of Life Quality-Adjusted Life Years Questionnaires
Severity of Illness Index Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).